LISTENER:AWSDLJIRLL002Z.JNJ.COM        : STATUS: The listener is down: TNS-12541: TNS:no listener .   
It was down due to db patch,application is up and running fine after the activity. 
 
EUROPE2-IS-BI-QA-A45: Database Patching	04-12-25 08:00	04-12-25 12:00	Unavailable	CHG000011337883